CYH33 (methanesulfonate)
Catalogue number:
HY-123938A-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1494684-33-1
Purity:
96.76
Molecular Weight:
694.7
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CYH33 methanesulfonate is an orally active, highly selective PI3Kα inhibitor with IC50s of 5.9 nM/598 nM/78.7 nM/225 nM against α/β/δ/γ isoform, respectively. CYH33 methanesulfonate inhibits phosphorylation of Akt, ERK and induces significant G1 phase arrest in breast cancer cells and non-small cell lung cancer (NSCLC) cells. CYH33 methanesulfonate has potent activity against solid tumors[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)