This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1293395-67-1
Purity:
99.56
Molecular Weight:
419.45
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-5006739 is a potent and selective inhibitor of CK1δ/ε with IC50s of 3.9 nM and 17.0 nM, respectively. PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 attenuats opioid agent-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner[1]. PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity[2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)