This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1834571-82-2
Purity:
99.87
Molecular Weight:
751.2
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AC-4-130 is a potent STAT5 SH2 domain inhibitor. AC-4-130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent gene transcription. AC-4-130 induces cell cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells. AC-4-130 has anti-cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)