This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2245887-38-9
Purity:
99.42
Molecular Weight:
585.8
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591 selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members[1].
Storage Temperature:
-20°C, 3 years (Powder)