δ-Secretase inhibitor 11
Catalogue number:
HY-124832-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
842964-18-5
Purity:
99.06
Molecular Weight:
220.23
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 µM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research[1].
Storage Temperature:
4°C (Powder, protect from light)