Dasminapant
Catalogue number:
HY-125593-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1570231-89-8
Purity:
99.36
Molecular Weight:
1157.4
Alternative Names:
APG-1387
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma[1][2][3][4][5].
Storage Temperature:
-20°C (Powder, stored under nitrogen)