PROTAC SGK3 degrader-1
Catalogue number:
HY-125878-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2381320-35-8
Purity:
99.02
Molecular Weight:
1157.38
Alternative Names:
SGK3-PROTAC1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on von Hippel-Lindau ligand. PROTAC SGK3 degrader-1 (0.3 µM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate)[1].
Storage Temperature:
-20°C (Powder, stored under nitrogen)