NPD-1335
Catalogue number:
HY-126250-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2376326-31-5
Purity:
98.1
Molecular Weight:
455.55
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death[1]. NPD-1335 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)