This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1260075-17-9
Purity:
99.97
Molecular Weight:
450.55
Alternative Names:
AG-348
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)