GSK143 (dihydrochloride)
Catalogue number:
HY-12736A-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2341796-81-2
Purity:
99.73
Molecular Weight:
415.32
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK143 dihydrochloride is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5. GSK143 dihydrochloride inhibits phosphorylated Erk (pErk: pIC50=7.1)[1]. GSK143 dihydrochloride reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice[2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)