This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1198784-72-3
Molecular Formula:
C23H25F4N3O4S
Molecular Weight:
515.52
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM[1]. BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC50>30 µM)[2]. BI 653048 is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[3].