This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2384184-40-9
Purity:
99.25
Molecular Formula:
C50H65ClN4O12
Molecular Weight:
949.52
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader (molecular glue). KB02-SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-SLF[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)