This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2384184-44-3
Purity:
98.24
Molecular Formula:
C38H43Cl2N7O6S
Molecular Weight:
796.76
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader (molecular glue), but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1[1].
Storage Temperature:
-20°C, 3 years (Powder)