Propargyl-PEG1-acid
Catalogue number:
HY-130504-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
55683-37-9
Purity:
97
Molecular Formula:
C6H8O3
Molecular Weight:
128.13
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib(HY-10997)-based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 µM[1]. Propargyl-PEG1-acid is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)