This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2250025-88-6
Purity:
99
Molecular Formula:
C44H51ClN10O9S
Molecular Weight:
931.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TL12-186 is a Cereblon-dependent multi-kinase PROTAC degrader. Multi-kinases include CDK, BTK, FLT3, Aurora kinases, TEC, ULK, ITK, et al. TL12-186 inhibits CDK2/cyclin A (IC50=73 nM) and CDK9/cyclin T1 (IC50=55 nM)[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture and light)