This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
309711-59-9
Purity:
99.83
Molecular Formula:
C19H19N3O2
Molecular Weight:
321.37
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC50 values ranging from 0.61 to 2.2 µM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)