This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2050524-24-6
Purity:
98.68
Molecular Formula:
C17H12ClN5O2S
Molecular Weight:
385.83
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)