This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2743427-26-9
Purity:
99.85
Molecular Formula:
C50H59F3N10O6S
Molecular Weight:
985.13
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader with a pDC50 of 8.4. GSK215 is designed by a binder for the VHL E3 ligase and the FAK inhibitor VS-4718. GSK215 induces rapid and prolonged FAK degradation, giving a long-lasting effect on FAK levels and a marked pharmacokinetic/pharmacodynamics (PK/PD) disconnect[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)