This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1834610-13-7
Purity:
95.37
Molecular Formula:
C530H712F10N173O320P43S6
Molecular Weight:
16339.007631.0+8708.0
Alternative Names:
ALN-G01
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2].
Storage Temperature:
-20°C (Powder, stored under nitrogen, away from moisture)