CCT128930 (hydrochloride)
Catalogue number:
HY-13260A-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2453324-32-6
Purity:
98.32
Molecular Formula:
C18H21Cl2N5
Molecular Weight:
378.3
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)