This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2470908-79-1
Purity:
98.5
Molecular Formula:
C37H35BrN4O3
Molecular Weight:
663.6
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
YS-370 (compound 44) is a potent, high selective, and orally active inhibitor of P-glycoprotein (P-gp). YS-370 stimulates the P-gp ATPase activity and has moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance (MDR) to paclitaxel and colchicine in SW620/AD300 and HEK293T-ABCB1 cells. YS-370 in combination with paclitaxel achieves much stronger antitumor activity[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)