This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
878437-15-1
Purity:
97.02
Molecular Weight:
342.35
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)