This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2559703-06-7
Purity:
99.24
Molecular Weight:
345.5
Alternative Names:
Apt-1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 µM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)