This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2230911-59-6
Purity:
98.86
Molecular Weight:
693.79
Alternative Names:
PD-1/PD-L1-IN-8
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
INCB086550 is a potent, oral, small-molecule PD-L1 inhibitor with IC50s value of 3.1, 4.9 and 1.9 nM for human, cynomolgus, and rat, respectively. INCB086550 promotes the dimerization of cell-surface PD-L1 and induces PD-L1 entry into Golgi vesicles then traffick to the nucleus. INCB086550 can be used for multiple cancers research[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)