N-Desmethyl-Apalutamide
Catalogue number:
HY-135331-1mL
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1332391-11-3
Purity:
99.68
Molecular Weight:
463.41
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)