I-OMe-Tyrphostin AG 538
Catalogue number:
HY-135680-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1094048-77-7
Purity:
99.34
Molecular Weight:
437.19
Alternative Names:
I-OMe-AG 538
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50 of 1 µM[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)