TRPC6-PAM-C20
Catalogue number:
HY-136190-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
667427-75-0
Purity:
99.9
Molecular Weight:
363.41
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca2+ concentrations ([Ca2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 µM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)