Fludarabine triphosphate (trisodium)
Catalogue number:
HY-136650A-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
95
Molecular Weight:
591.12
Alternative Names:
F-ara-ATP (trisodium)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 µM and a Ki of 6.1 µM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis[1][2].
Storage Temperature:
-20°C (Powder, protect from light, stored under nitrogen)