This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2117405-13-5
Purity:
97.01
Molecular Weight:
338.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
SEN177 is a potent glutaminyl cyclase (QPCT) inhibitor with an IC50 of 0.013µM for glutaminyl-peptide cyclotransferase-like (QPCTL). SEN177 has a Ki of 20 nM for human glutaminyl cyclase (hQC). SEN177 greatly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates. SEN177 has the potential for Huntington’s disease research[1].
Storage Temperature:
-20°C, 3 years (Powder)