Flumatinib (mesylate)
Catalogue number:
HY-13905-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
895519-91-2
Purity:
99.87
Molecular Weight:
658.69
Alternative Names:
HHGV678 mesylate
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Flumatinib (HHGV678) mesylate is an orally active and selective inhibitor of Bcr-Abl. Flumatinib mesylate inhibits c-Abl, PDGFRβ and c-Kit with IC50 values of 1.2, 307.6 and 665.5 nM, respectively. Flumatinib mesylate inhibits Bcr-Abl autophosphorylation and Stat5 and Erk1/2 phosphorylation. Flumatinib mesylate inhibits tumor growth in chronic myelogenous leukemia model[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)