NMDAR/TRPM4-IN-2 (free base)
Catalogue number:
HY-139192A-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1353979-43-7
Purity:
99.24
Molecular Weight:
257.17
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NMDAR/TRPM4-IN-2 free base (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 free base shows neuroprotective activity. NMDAR/TRPM4-IN-2 free base prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 µM. NMDAR/TRPM4-IN-2 free base protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)