This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2648641-36-3
Purity:
95.73
Molecular Weight:
447.41
Alternative Names:
TPX-0131
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Zotizalkib (TPX-0131) is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK (IC50 of 1.4 nM) and ALK-resistant mutation, e.g. G1202R (IC50 of 0.3 nM), L1196M (IC50 of 0.3 nM). Zotizalkib has strong antitumor activities[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)