PD-L1-IN-1
Catalogue number:
HY-139781-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2767424-13-3
Purity:
99.53
Molecular Weight:
377.44
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter. PD-L1-IN-1 significantly increased interferon γ release and apoptotic induction of cancer cells, with low cytotoxicity in healthy cells[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)