This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2369048-69-9
Purity:
98.93
Molecular Formula:
C29H31NO4
Molecular Weight:
457.56
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNE-274 is a non-degrader that is structurally related to GDC-0927 (ER degrader). GNE-274 does not induce ER turnover and functions as a partial ER agonist in breast cancer cell lines. GNE-274 increase chromatin accessibility at ER-DNA binding sites, while GDC-0927 do not. GNE-274 is a potent inhibitor of ER-ligand binding domain (LBD). GNE-274 can be used for cancer research[1][2].
Storage Temperature:
4°C (Powder, protect from light, stored under nitrogen)