This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2729996-45-4
Purity:
98.28
Molecular Formula:
C26H22FN5O2
Molecular Weight:
455.48
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers[1].
Storage Temperature:
-20°C, 3 years (Powder)