GNF2133 (hydrochloride)
Catalogue number:
HY-142295A-25mg
Supplier:
Size:
25 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2561414-57-9
Molecular Formula:
C24H31ClN6O2
Molecular Weight:
470.99
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNF2133 hydrochloride is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0.0062, >50 µM for DYRK1A and GSK3β, respectively. GNF2133 hydrochloride shows good proliferation potency and efficacy on rat and human primary β-cell. GNF2133 hydrochloride significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 hydrochloride has the potential for the research of type 1 diabetes[1].