MPP+-d3(iodide)
Catalogue number:
HY-W008719S-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
207556-07-8
Purity:
99.6
Molecular Weight:
300.15
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MPP+-d3 (iodide) is deuterium labeled MPP+ (iodide). MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2].
Storage Temperature:
4°C (Powder, protect from light)