BMS-986260
Catalogue number:
HY-W107024-1mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2001559-19-7
Purity:
98.03
Molecular Weight:
382.78
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BMS-986260, an immuno-oncology agent, is a potent, selective, and orally active TGFβR1 inhibitor (IC50=1.6 nM). BMS-986260 displays exquisite selectivity for TGFβR1 over its isozyme TGFβR2, as well as in a panel of more than 200 kinases examined. BMS-986260 inhibits TGFβ mediated nuclear translocation of pSMAD2/3 in MINK and NHLF cells lines with an IC50 of 350 nM and 190 nM, respectively[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)