Azido-PEG4-Val-Cit-PAB-MMAE
Catalogue number:
HY-W190943-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1869126-64-6
Purity:
99.36
Molecular Weight:
1396.71
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH[1]. Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Storage Temperature:
-20°C (Powder, protect from light, stored under nitrogen)