NF-κB Reporter (Luc) - HEK293 Recombinant Cell line

The NF-κB reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-κB) activity. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-α, IL-1β, and IL-17. This product is for research use only and is subject to a Limited Use License. For your order to be processed, you will be required to complete a Limited Use License Agreement form at: https://bpsbioscience.com/license/agreement/form, ensuring you state your Purchase Order number when asked for Sales Order/Quote #. Further information can be found at: https://bpsbioscience.com/license.

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