KRAS (G12D), Isoform A, His-Tag, GppNHp-Loaded Recombinant
Catalogue number:
BPS-101481
Supplier:
Size:
4 x 60 µg _$$_
Product is available in:
Product Description:
Recombinant human KRAS (KRAS proto-oncogene GTPase), isoform a, encompassing amino acids 2-186(end). This construct contains an N-terminal His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease, BPS Bioscience #50308). The protein also contains mutation of interest G12D. The protein was affinity purified and loaded with GppNHp, a non-hydrolyzable GTP analog. Unbound GppNHp was removed by spin column. Ready for use in KRAS-RAF binding studies or inhibitor assays.
Storage Temperature:
At least 6 months at -80°C.
