Tubastatin A hydrochloride
Catalogue number:
BPS-27108
Supplier:
Size:
10 mg _$$_
Product is available in:
Product Description:
Tubastatin A is a potent HDAC6 inhibitor. It demonstrates over 1,000-fold selectivity against all other HDAC isoforms (IC50 >16 µM), excluding HDAC8 (IC50 = 0.9 µM). Tubastatin A induces a-tubulin hyperacetylation at 2.5 µM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, it displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 µM.
Storage Temperature:
Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored a
