GITR / NF-κB Luciferase Reporter - Jurkat Cell Line

This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene; TNFRSF18; CD357) and an NF-κB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody. This product is for research use only and is subject to a Limited Use License. For your order to be processed, you will be required to complete a Limited Use License Agreement form at: https://bpsbioscience.com/license/agreement/form, ensuring you state your Purchase Order number when asked for Sales Order/Quote #. Further information can be found at: https://bpsbioscience.com/license.

• Data sheet: View or download