1,10-Phenanthroline, Monohydrate
Catalogue number:
BPS-27713
Supplier:
Size:
0.5 ml _$$_
Product is available in:
CAS Number:
5144-89-8
Purity:
≥99%
Molecular Weight:
198.2
Product Description:
1,10-phenanthroline (o-phenanthroline) is a chelator with high affinity for divalent metal ions. When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.
Storage Temperature:
Store powder at room temperature. Store ethanol or methanol stock solutions at -20°C. Aqueous soluti