GSK-872
Catalogue number:
HY-101872-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1346546-69-7
Purity:
99.91
Molecular Weight:
383.49
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury[1][2][3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)