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103883-03-0
≥98%
A solid
576.5
(2r,3s,8s,14r,15r)-2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2h,14h-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, epicatechin-(4β→8,2β→o→7)-catechin, proanthocyanidin a1, procyanidol a1
- Data sheet: View or download
- MSDS: View or download
A polyphenol flavonoid dimer with diverse biological activities; binds to PlGF and VEGF (Kds = 394 and 476 nM, respectively); increases the activity of JAK2 (EC50 = 660 nM); scavenges superoxide radicals (IC50 = 14.7 µM); inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 = 14 µg/ml); increases the proliferation of isolated mouse splenocytes and peritoneal macrophages from 25-100 µM and DAMI megakaryoblasts (EC50 = 8.58 µM); prevents decreases in the number of platelets in peripheral blood and megakaryocytes in the bone marrow in a mouse model of carboplatin-induced thrombocytopenia at 50 mg/kg
-20°C