D-erythro Lysosphingomyelin (d18:1)
Catalogue number:
CAY10007947-5 mg
Supplier:
Size:
5 mg
Product is available in:
£520.00
Estimated delivery Fri 2 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1670-26-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
464.6
Alternative Names:
2-[[[[2s-amino-3r-hydroxy-4e-octadecenyl]oxy]hydroxyphosphinyl]oxy]-n,n,n-trimethyl-ethanaminium, d-erythro lyso sm(18:1), d-erythro sphingosine-1-phosphocholine (d18:1), d-erythro-sphingophosphorylcholine, lyso-sm(d18:1), lysosphingomyelin (d18:1)
- Data sheet: View or download
- MSDS: View or download
Product Description:
A bioactive sphingolipid; agonist of S1P1, S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors); agonist of ORG1 that induces calcium accumulation in cells overexpressing OGR1 (EC50 = ~35 nM); levels are increased in skin isolated from patients with atopic dermatitis, as well as postmortem brain from patients with Niemann-Pick disease type A
Storage Temperature:
-20°C
