£418.00
Estimated delivery Tue 30 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
287714-41-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
481.5
Alternative Names:
7-[4-(4-fluorophenyl)-6e-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3r,5s-dihydroxy-6-heptenoic acid, zd 4522
- Data sheet: View or download
- MSDS: View or download
Product Description:
An HMG-CoA reductase inhibitor (IC50 = 5 nM); inhibits cholesterol synthesis in isolated rat hepatocytes (IC50 = 0.16 nM); reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet at 10 mg/kg; decreases the area of aortic atherosclerotic lesions in the same model
Storage Temperature:
-20°C
