£105.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
170729-80-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
534.4
Alternative Names:
5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3h-1,2,4-triazol-3-one, emend, l-754,030, mk-869, ono-7436
- Data sheet: View or download
- MSDS: View or download
Product Description:
An antiemetic and NK1 antagonist (Ki = 3 nM; IC50 = 0.09 nM for the human receptor); selective for NK1 over NK3 receptors (Ki = 454.1 nM for human NK3); prevents substance P-induced plasma extravasation into the esophagus of guinea pigs at 1 mg/kg; reduces NK1-agonist-induced foot tapping in gerbils
Storage Temperature:
-20°C
