ABT-263
Catalogue number:
CAY11500-1 mg
Supplier:
Size:
1 mg
Product is available in:
£34.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
923564-51-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
974.6
Alternative Names:
4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-n-[[4-[[(1r)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-benzamide, a-855071, navitoclax
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of Bcl-2 family proteins (Kis = is = 550 and 354 nM, respectively); cytotoxic in a panel of SCLC, leukemia, and lymphoma cell lines (mean EC50 = 1 µM); induces apoptosis in influenza A-infected retinal pigment epithelial cells (EC50 = 0.08 µM); induces tumor regression in NCI H146 SCLC and RS4;11 ALL mouse xenograft models at 100 mg/kg
Storage Temperature:
-20°C
